Tuesday 18 June 2019

OPTICS AND INSTRUMENTS (Adequate for an ophthalmologist)



- Amsler grid: each square is 1 degree at 33 cm
- 1 M unit (1.54mm) is 1 minute of angle at 1 meter
- 1 20/20 Snellen letter is 5 minutes at 6 meters
- resolution of Snellen letter is 1 minute at 6 meters (i.e. 6M)
- resolution of Snellen letter is 6M
- each 20/20 Snellen letter is 30M
Goldman 3 mirrors: 59-67-73 (gonio is 59)
Fluorescein:
excitation: 490
emission: 520
filter: 500
ICG: 835?
DDx of monocular diplopia
1) astigmatsm
2) keratopathy
3) cataract
4) subluxated lens
5) iris atrophy
6) vitreous disease
7) iridectomy
8) malingering
Steep (“tight”) contact lens
1) fluctuating acuity
2) better acuity with blink (moves liquid out)
3) more comfortable
4) poor nutrient exchange
5) persistant astigmatism
6) CL doesn’t fall out
7) little mvt with blink
8) central hypoxia (microcystic edema, PEK)
9) lens low
10) symptoms: burning, photophobia, tearing
11) congested vessels
12) corneal vascularization (pannus)
Signs of flat contact lens
1) clear vision
2) worse acuity with blink (moves)
3) discomfort
4) nutrient exchange adequate
5) no astigmatism
6) lose CL easily
7) movement with blink
8) central corneal abrasion (stain)
9) lens high
10) symptoms: f.b. sensation
Change that can be made on a CL
1) flatten peripheral curve
2) PMMA lenses: adjust power by +/- 0.50 D
Treatment of prismatic effect of ADD
A) Prismatic effect
1) slab-off more myopic lens (BU effect)
2) reverse slab off hyperopic side (BD effect)
3) Fresnel vertical prisms
4) permanent vertical prisms lens
B) Types of add
1) round top for some plus lens (executive)
2) flat top for some plus lens (waiter) - no jump
- makes prismatic effect worse
3) flat top for minus
4) dissimilar segments (eg. round and flat)
C) Centration
1) different center for each lens (bicentration)
2) decenter both distance lenses downward
3) raise ADD closer to center
D) Different pairs
1) contact lenses
2) separate reading glasses
Prentice Rule
- to correct, assume eye looks down 8mm and nasal 2mm
Increased with the rule astigmatism post-op
1) tight sutures
2) many sutures
3) deep bites
4) long bites
5) anterior incision
6) fine sutures (eg. 10-0) - don’t loosen
7) non-absorbable sutures
Contact lens correction
- soft originally for sports, occasional wearers, occasional overnite wearers
- now, for 90% of CL wearers
- RGP better for astigmatism, young progressing myopes
- mulifocals: distance CL for dominant eye; near for non-dominant eye
Types of multifocals contact lenses
1) multifocal aspheric, near in center (soft and hard)
2) bifocal near below
3) multifocal in periphery which moves when eye looks at near to center over pupil (CL moves)
4) diffractive lenses
Types of multififocal IOL’s
1) multifocal aspheric, near in center (soft and hard)
2) distance- near - distance ( 3 rings)
3) diffractive
4) bifocal below?
6 ways to use slit lamp
1) diffuse
2) slit beam
3) indirect - turn knob on arm
4) sclerotic scatter
5) retroillumination
6) specular reflection
Ultrasound wavelengths
1) A scan: 8-15 MHz “reflective”
2) B scan: 8-15 MHz “echogenic”
3) UBM: 50-100 MegaHz
Ultrasound lesion description
1) shape
2) echogenicity
3) homogeneity (regularity)
4) vascularity (dynamic) - seen in melanoma, not angioma or mets
5) dynamic movement: eg RD, PVD
Decrease meridional magnification by
1) decrease cylinder power
2) rotate axis to 90 or 180
3) decrease vertex distance
4) minus cylinder lenses
5) consider CL
Lens Aberrations
1) Spherical aberration
- the most important aberration in the eye
- increases with the 4th power of the pupil
- image is focused anterior to expected location
- increase as object moves away from optical axis
2) Coma
- cause rays from a point to be focused over a small area
- increase as object moves away from optical axis
3) Off-axis astigmatism
- increase as object moves away from optical axis
4) Chromatic aberration
- blue is bent more than red
- yellow sits on retina
- red-blue interval: 1.50 D
- red-green interval: 0.50 D
5) Curvature of Field
- image focused on cuved surface
- advantageous in the eye (only one)
6) Distortion
- different points of the object are magnified dif’t amounts
- e.g. pincushion, barrel distortion
7) Astigmatism of oblique incidence
- tilting of lens
Ways eye deals with spherical aberration
1) pupil
2) cornea is aspheric (greater central refraction)
3) nucleus center is more refractive
Accomodation Amplitudes
0 : 18
10: 14
20: 10
30: 8
40: 6
50: 3
60: 1.5
70: 0
Retinoscopy
A) power
- as we approach neutrality, streak is
1) brighter
2) faster
3) fatter
B) axis
- as we approach correct axis, there is
1) less break
2) less skew
3) thinner reflex
4) brighter intensity
Ultraviolet wavelengths
1) UVA: 320-400 - 90% on earth
2) UVB: 280-320 - 10% on earth
3) UVC: <280 - negligeable
Sunglasses: (p. 224 AAO)
1) improve color contrast
2) improve dark adaptation
3) reduction of glare sensitivity (eg. polarized)
4) UV absortion
5) photochromic change with light (silver ions - UV)
UV absorbtion
1) almost all dark sunglasses
2) coated glass (clear glass transmits all above 300nm)
3) plastic made of polycarbonate and CR-39 (transmits above 350; partial absorption)
Regular lenses must
1) be at least 2mm thick
2) withstand 5/8 inch steel ball dropped from 50 inches
Industrial lenses must
1) be at least 3 mm thick
2) withstand 1 1/8 inch steel ball dropped from 50 inches
Lens material
1) glass (high density, high index)
2) high density glass
3) plastic (low density, low index)
4) high density plastic
5) polycarbonate (low density high index)
When to prescribe polycarbonate lenses
(AAO p.229); - “shatter proof”?
- discovered in 1950’s
- lighter, stronger lenses
1) sports
2) industrial
Components of Hyperopia
1) Total: Manifest + Latent
2) Manifest: Absolute + Facultative
AC/A ratio
1) normal = 4-6
2) heterophoria method:
IPD (cm) + [ET (dist) - ET (near)]/near (D)
3) clinical distance-near relationship (usual);
compare deviation at near and far (> 10 abnormal)
4) lens gradient: compare with no lens and with
+ 3.00 at near (or other variations of manipulating with lenses)
Prisms for low vision glasses
- 2 PD BI more than prescription
eg. + 10 D glasses: +12 PD BI OU
after + 10 single vision; available up to + 40
Lensometer: prism moves rings towards base (1 ring per PD)
Advantage of spectacles
1) Both hands free
2) large field
3) Don’t have to hold something
4) good for hand tremor
5) binocular
Advantage of hand lens
1) variable magnification
2) compact
3) esthetic
Disadvantage of projector
1) poor contrast
2) fixed distance
Advantage of Keplerian telescope
1) greater magnification
2) greater focusability
Advantage of Galillean
1) easier to use
2) smaller
3) field expander
Correction of aphakic anisoconia
1) CL
2) decrease vertex of spectacles
3) IOL insertion
4) overcorrected plus CL with minus spectacle lens
5) minus cylinder spectacle lenses
6) decrease lens convexity?? (notes)
Fresnel lens uses
A) prism
1) adaptation test (pre-op surgery in adult)
2) correction of temporary deviation
3) exercises for X(T)
4) stable incomitant deviations
5) nystagmus (null point)
6) VF defects
B) plus lens
1) penalization
2) accomodative ET’s
3) temporary aphakia
4) occupational bifocal adds
5) low vision high power segments
C) minus lens
1) X(T) treatment
Multifocal lenses
1) unwanted astigmatism in area lateral to progressive corridor
Aphakic lens problems
1) ring scottooma
2) jack in the box
3) pincushion distortions
Types of plastic frames
1) CR-39
2) MMA (Plexiglass)
3) Celluloid (cellulose)
4) Nylon
5) carbon-nylon
6) carbon graphite
Types of Metal frames
1) gold
2) aluminum
3) titanium
4) stainless steel
5) “nickel/silver” (German silver - nickel + copper + zinc)
Ways to hold CL in place
1) prism ballast
2) truncation
3) myoflange (plus lenses)
4) lenticular bevel ( minus lens)
Automated Refractors Metjhods
1) optometer
2) Scheiner principle (2 holes)
3) laser speckle pattern movement
4) photo of retina (screening)
5) VEP
6) automated phoropter
7) automated refracting lane
Low Vision Aids
A) Near
1) high plus glasses with BI prism
2) hand-held magnifying lens
3) stand magnifier
B) Far
1) Galilean telescope
2) astronomical telescope
C) Increase field
1) reverse Galilean telescope
D) Non-optical
1) monitor
2) large print books
3) good lighting
4) tinted glasses (improves contrast
5) computers which scan text
6) audiible books


Saturday 15 June 2019

ANATOMY/ EMBRYOLOGY OF THE EYE - QUICK EXAM TYPE REVISION


Lateral orbital tubercle insertions (Whitnall’s tubercle?)
1) check ligaments of LR
2) lateral horn aponeurosis of levator
3) orbital septum
4) lateral canthal tendon
5) Lockwood’s ligament
(Whitnall’s ligament inserts at trochlea and between lacr. gland lobes)
Lockwood’s ligament: connects IO capsule to IR capsule and to lower lid retractors
Whitnall’s ligament: where levator aponeurosis originates?
Walls of orbit
Medial (4): ethmoidal, lacrimal, maxilla, sphenoid
Floor (3): maxilla, zygoma, palatine
Lateral (2): zygoma, greater wing of sphenoid,
Roof (2): frontal, lesser wing of sphenoid
- NB: sphenoid everywhere except floor
MOST/LEASTS
Sclera:
- thinnest at EOM insertions
- thickest:posteriorly
Goblet cells:
- most at plica and caruncle
- absent at limbus
Embryonic Derivatives
A) ectoderm
1) lid skin epithelium and appendages
2) conj epithelium
3) lens
4) lacrimal gland
5) lacrimal drainage (puncta, canal., sac, NLD)
6) primary vitreous
B) neuroectoderm
1) neurosensory retina
2) RPE
3) ciliary epith. (both layers)
4) iris sphinter and dilator
5) optic nerve
C) mesoderm
1) endoth. of all blood vessels
2) EOM’s
3) temporal sclera
D) neural crest: THE REST
A) Orbit
1) orbit c.t.
2) orbital bones
3) trochlea
4) meningeal sheath of O.N.
5) ciliary nerve Schwann cells
6) EOM tendons
B) Globe
1) sclera
2) cornea stroma and endoth.
3) choroid
4) c.b. muscle
5) t.m.
6) iris stroma
7) melanocytes
8) 2nd and 3rd vitreous
Development dates:
Lens (Day 25-40 or Week 4-6)
Day:
25: optic vesicle
27: lens plate
29: lens pit (after 4 weeks)
33: lens vesicle
35: primary lens fibers (after 5 weeks)
40: lens is obliterated (after 6 weeks)
40-240: secondary lens fibers
56: Y sutures (2 months)
9 month: pupil mb disappears
Glaucoma
8 month: angle formed
Nerve
at birth: myelination to lamina cribosa (AAO)
7 month to 2 years after birth (Wright) - full
myelinization?
Retina
5 weeks: retinal pigment
8 months: nasal retinal vascularization
at birth: temporal retinal vascularization
4 months post-natal: macula
Hyaloid fissure
week 5: hyaloid artery enters fissure –when lens
develops
week 6-8: closure (Moore)
month 8: regression
Comparisons
Structure New born Adult
globe length 16 24
cornea diam. 9.5-10 11
Sinus formation
1) maxillary: birth (jaw)
2) ethmoid: birth (nose)
3) frontal: 6 years (forehead)
4) sphenoid: slowly; complete around early puberty (brain)
A) Ciliary ganglion
A) Roots
1) V1 sensory root is the long ciliary nerve; branch of nasociliary nerve
2) parasympathetic root is from the inferior division of CN 3
3) sympathetic root is from internal carotd
B) Branches
1) short ciliary nerves; contain:
a) parasympathetic innervation to iris and c.b.
b) sympathetic innervation to iris and c.b., vessels
c) sensory innervation of globe (iris, cornea)
Numbers
A) Retina
1) 1.2 million axons
2) 6 million cones
3) 120 million rods
4) 5 million RPE cells
B) Arteries and nerves
1) 6-10 short ciliary nerves
2) 2 long ciliary nerves (sensory from NC n.) - sensory innervation to anterior eye
3) 20 short post. cil. arteries
4) 2 long posterior ciliary arteries
5) 7 anterior ciliary arteries (LR has one)
6) intraorbital optic nerve: 25 mm (1 inch)
7) intracranial optic nerve: 10 mm (1 cm)
C) Lens
1) lens: 9.5 mm at equator
2) bag after extraction: 10.5 mm
3) sulcus: 11.5 mm
4) zonules insert 1.5 mm from equ. ant surface
5) zonules insert 1.25 mm from equ. Post surface
Attachments of uvea
1) optic nerve
2) scleral spur
3) vortex veins
Attachments of vitreous
1) optic nerve
2) vitreous base
3) macula
4) retinal vessels
Attachments of Tenon’s
1) 3 mm posterior to limbus
2) around optic nerve
Vortex veins
1) in eye: ampulla are seen at equator (where they exit the choroid)
2) on sclera: seen near nasal and temporal margins of IR and SR muscles
3) have an oblique course within the sclera
Structures in vertical saccades
A) Origin
1) frontal cortex
2) superior colliculus
B) Secretaries (Neil Miller) - premotor regions
1) riMLF - rostral internucleus of the MLF(midbrain) - just posterior to the red nucleus
2) interstitial nucleus of Cajal
Structures in horizontal saccades
A) Origin
1) frontal cortex: contralateral
2) superior colliculus
B) Secretaries (Neil Miller) - premotor regions
1) PPRF: ipsilateral gaze
2) MLF: contralateral gaze
Structures in vertical and horizontal pursuit
A) Origin
1) Occipital cortex
B) Middle men
2) visual association areas (MT, MST)
3) parietal cortex: ipsilateral
C) Secretaries
1) pontine nuclei
2) cerebellum
3) vestibular nuclei
Supranuclear Anatomy (Basic)
A) Origin
1) frontal lobe: contralateral saccades
2) parietal lobe: ipsilateral pursuit
B) Secretaries
1) PPRF: ipsilateral gaze
2) MLF: contralateral gaze (as soon as it leaves PPRF, it crosses)
Clivus: bone from from foramen magnum until dorsum sella; includes sphenoid and occipital bone
Blood Supply
A) Globe
1) optic nerve head: cenral retinal artery
2) prelaminar region: posterior ciliary arteries
3) lamina cribosa: posterior ciliary arteries
4) post-laminar region: pial branches of CRA
B) Behind globe
1) orbital optic nerve: ophthalmic artery
2) intracanalicular optic nerve: ophthalmic artery
3) intracranial optic nerve: ICA, ACA, ant. comm. artery
4) chiasm: ICA, anterior comm. art.
5) optic tract: anterior choroidal artery
6) LGN: anterior and posterior choroidal art.
7) optic radiations MCA and PCA
8) occipital cortex: MCA and PCA
ICA/ECA arterial anastomosis
1) the 2 intracavernous ICA’s are in communication with the meningeal arterial
system arising from the 2 ECA’s
i) ascending pharyngeal artery
ii) internal maxillary artery
2) lacrimal artery anastomoses with branches of the external carotid system at 2 or (sometimes) 3 sites
i) middle meningeal artery
ii) anterior deep temporal artery
iii) infraorbital artery (sometimes)
Iris stroma
1) melanocytes
2) clump cells
3) chromatophores
Le forte Fracture which involves floor: 2 and 3
Drusen
<64: small
65-125: medium
>125 large

Wednesday 12 June 2019

Ocular syndromes



Acute angle closure glaucoma
1) cornea: endothelial damage
2) iris: atrophy, PAS, and post synechia
3) lens: glaucomflecken, cataract
4) c.b.: hyposecretion
5) optic nerve: atrophy, no cupping
Aniridia
- AD: 2/3; sporadic: 1/3
- 1/60000
- chromosome 11
- VA < 20/200
- assoc: Wilm's, MR, GU abn.
- U/S or IVP every 3 months
Signs
1) cornea: pannus (epithelial metaplasia), keratoconus (Duanes’)
2) angle: angle closure glaucoma
3) iris: hypoplasia
4) lens: subluxation, cataract
5) retina: foveal hypoplasia
6) optic nerve: hypoplasia
7) neuro: nystagmus
8) EOM: strabismus
Anterior Segment dysgeneses
A) Post. embryotoxon
- AD
- anterior displaced Schwalbe’s line
B & C) Axenfeld-Rieger Syndrome
- new terminology
- AD (75%); 25% sporadic
- bilateral but asymmetric
B) Axenfeld Anomaly
i) Ocular
1) posterior embryotoxin
2) iris process to Shwalbies Lline
3) glaucoma (“Axenfelds’s syndrome”)
ii) Systemic
1) MSK abnormalities
C) Rieger's
i) Ocular
1) Axenfeld's
2) iris stroma defects
3) glaucoma (50%)
4) corectopia
5) ectropion uvea
6) PAS
7) pseudopolycoria
ii) Systemic (“Rieger’s syndrome”)
1) facial, skeletal, dental abnormalities
2) umbilical hernia and redundant skin
D) Peter’s
- AD, AR or sporadic
- bilateral: 80%
A) Ocular
1) loss of central Decemet’s and endothelium
2) +/- lens sticking to stroma
3) glaucoma (50%)
B) Systemic (“Peter’s plus” syndrome)
1) cardiac defects
2) cleft lip/palate
3) MSK defects
4) craniofacial anomalies
E) Von-Hippels internal ulcer
- Peter’s associated with intrauterine inflammation
- may see uveitis, KP’s, pannus after birth
F) circumscribed posterior keratoconus
- localized indentation of posterior cornea
- unilateral
- sporadic
Benign papillophlebitis
1) unilateral
2) normal field
3) normal acuity
4) like partial CRVO
5) peripheral retinal NFL heme
6) resolves on its own
7) young people
Best’s Disease
- AD
- EOG abnormal with normal ERG
- lipofuschin deposits
Stages:
1) RPE changes
2) yolk
3) scrambled or fried egg
4) pseudohypopion
5) atrophy
Blepharitis (Rosacea) - type IV response
A) Systemic
1) skin telangiectasias
2) rhinophyma
3) skin pustules
4) fair skinned
5) skin erythema
6) skin papules
7) hypertrophic sebaceous glands
8) malar rash
9) flushing with alcohol, coffee
B) Lid
1) m.g. plugging
2) debris (scurf)
3) lid thickening (tylosis)
4) chalazia
C) Ocular
1) conjunctivitis
2) corneal pannus
3) punctate epithelial erosions
4) dry eye
5) peripheral infiltrates (10:00, 2:00, 4:00, 8:00)
6) sterile ulcer
7) episcleritis
8) iritis
Blepharitis (Staph)
- F>M
A) Lid
1) poliosis, trichiasis, madaurosis
2) ant. blepharitis
3) collarettes
4) lid ulceration
5) lid thckening (tylosis)
B) Ocular
1) phlyctenules (rxn to staph cell wall Ag)
2) marginal infiltrates (spade-shape)
3) pannus
4) conjunctivitis
5) dry eye
Carotid-Cavernous fistula (CCF)
- head trauma: 75% (Young)
- spontaneous: 25% (old)
A) anterior segment
1) injected conjunctival and episcleral vessels (corkscrew)
2) elevated IOP
3) anterior segment ischemia in 20% (cells, flare, corneal edema, cataract, rubeosis)
B) Posterior segment
1) CRVO
2) ocular ishemic syndrome?
C) Orbit
1) pulsating proptosis
2) enlarged EOM’s
3) CN 6 palsy (compression in cav. sinus): 50%
4) CN 3, 4 palsy less common
8) bruit
Central Areolar Dystrophy
1) AD
2) symptoms start at 40-50
3) decreased ERG and EOG
Ciancia syndrome
1) large ET
2) cross fixate
3) nystagmus when fixing eye abducts
4) often undercorrected
5) need large recessions
CSNB
- 3 types: XL, AD, AR
1) vision 20/20 to 20/200
2) no nystagmus
3) poor nite vision
4) problem with on/off connections
Diabetes ocular findings (less known)
A) Ant segment
1) decreased corneal sensation
2) dry eye
3) corneal opacity
4) epithelial abnormalities
5) Descemet’s folds (“wrinkles”)
6) ectropion uvea
7) xanthelasma
B) Posterior segment
1) sheathing
2) Roth spots
3) macular dragging
4) diabetic papillopathy
5) lipemia retinalis (white vessels from fat)
6) c.b. b.m. thickening
7) choriocapillaris b.m. thickening
8) asteroid hyalosis
Ectopia lentis et pupillae - AR
1) large cornea
2). lens and pupil move opposite dir
3) cataract
4) iris transillumination
5) poor dilation
6) slit pupil
7) RD
8) high myopia
Esotropia (Infantile, congenital, essential)
1) deviation > 30 PD
2) FH common
3) DVD (75%)
4) latent nystagmus (50%) - horiz or rotat.
5) IOOA (70%)
6) amblyopia (50%)
7) cross-fixating
8) assymetric OKN’s
9) monocular smooth pursuit asymmetry
Esotropia (Accomodative)
1) onset 6 months - 7 years
2) usual 2 - 3 years
3) heraditary
4) hyperopes (+3 to +10; average = +4)
5) amblyopia
6) most common ET
7) ET moderate (20-30 PD)
8) near-distance difference < 10 PD
Exfoliation syndrome
1) peripupillary atrophy
2) deposits: lens, cornea, iris, conj, c.b., zonules, angle
3) increased pigment dispersion with dilation
4) weak zonules
5) may result in CACG as well as COAG
6) prevalence of glaucoma:7% and OHT 15% (Yanoff study)
7) normal response to steroids (25% vs 90% in COAG)
8) W > B
9) often unilateral
Fuch’s iridocyclitis
1) stellate KP’s
2) unilateral (usually)
3) minimal AC reaction
4) vitritis
5) heterocheomia
6) no synechia
7) cataract
8) glaucoma
Giant Papillary Conjunctivitis
1) CL intolerance
2) discharge
3) blurred vision
4) conj injection
5) papillae > 0.3 mm
6) bloody tears
7) ptosis
8) lens displaced
Goldman Favre - AR
1) cataracts
2) peripheral and foveal retinoschisis
3) RP-like changes
4) optic atrophy
Gyrate Atrophy - AR
- classic scalloped RPE lesions
1) myopia
2) cataract (PSCC)
3) night blindness at 10 y.o.
4) present to MD at 20-30 y.o.
5) decreased VA
6) decreased VF
7) extinguished ERG
8) ornithine levels increased 10 fold
9) B6, diet control
ICE syndromes
1) unlateral
2) F > M; W > B
3) epithelialization of endothelium (seen with specular microscopy)
4) PAS
5) corectopia
6) iris atrophy (greatest in progressive iris atrophy)
7) corneal edema (greatest in Chandler’s)
8) young age
Keratoconus
signs
1) Munson’s sign
2) Rizzuti’s sign
3) Fleisher ring
4) Vogt’s stria
5) breaks in Bowman’s
6) enlarged corneal nerves
7) hydrops
Lattice Dystrophy
1) AD
2) recurrence in graft: lattice > granular > macular
Leber’s Congenital Amaurosis
- AR
- 2-3 months of age when noticed
- absence of rods and cones
- oculodigital reflex
A) Ocular
1) cataracts
2) glaucoma
3) paradoxical pupils
4) RP-like changes
5) blond fundus
6) macular atrophy
7) vessel attenuation
8) pigmentary retinopathy
9) optic nerve pallor
10) sensory nystagmus
11) hyperopia
B) Systemic
1) renal anomalies
2) MSK anomalies
3) brain anomalies
Megalocornea
- XL (90% male)
A) Systemic Asociations
1) MR
2) craniosyntosis
3) Down’s
4) Alport’s
5) Marfan’s
6) short stature
7) frontal bossing
B) Ocular associations
1) 13-16 mm corneas
2) cataract
3) ectopia lentis
4) goniodysgenesis
5) microcoria
6) miosis
7) glaucoma
8) lipid arcus
Microcornea
- AD and AR
A) Systemic Associations
1) myotonic dystrophy
2) fetal alcohol
3) Ehlers Danlos
B) Ocular associations
1) PHPV !
2) cataracts
3) goniodysgenesis
4) ON hypoplasia
5) ACG
6) COAG
Monofixation (microtropia) Syndrome
A) Findings
1) ET less than 8 PD on cover-uncover
2) deviation may be > 10 PD on alternate cover
3) amblyopia (usually slight)
4) macular scotoma on binocular testing
5) poor stereopsis
6) central scotoma, peripheral fusion
7) ARC (extramacular)
8) normal cover/ uncover
9) usually abnormal 4 base out prism test
B) Causes
1) strabismus (corrected)
2) anisometropia
3) amblyopia
4) macular scar
Mooren’s ulcer
precipitating factors: surgery, trauma, or parasite
A) Limited Type
1) unilateral (75%)
2) older patients
3) M=F
4) slow course
5) mild pain
6) responds to treatment
B) Progressive Type
1) bilateral (75%)
2) young, black (nigerian)
3) males
4) rapidly progressive
5) severe pain
6) poor response to treatment
Nonarteritic AION
1) older
2) visual loss less severe
3) 2nd eye affected in 25%
4) hypertension and DM associated
5) 5-10% progress over 2-3 weeks
Oculomotor Apraxia
A) Findings
1) M > F
2) inability to generate horizontal saccades
3) vertical saccades normal
4) head thrust past target and then refixate
5) VOR impaired
6) OKN abnormal
7) congenital type may improve with age
B) Associations and Causes
1) idiopathic
2) corpus callosum agenesis
3) hydrocephalus
4) cerebellar lesion
5) bilateral lesions of frontoparietal cortex -need CT!
Optic pit
1) usually unilateral (85%)
2) serous RD (40%)
3) disc may be large
4) macular holes
5) retinal hemorrhages
6) presents age 20-40
7) FA leakege
8) theories on source of fluid:
i) vitreous (most likely)
ii) choriocapillaris
iii) CSF
iv) macular hole
perifoveal telangiectasias
I) unilateral parafoveal
- congenital and acquired
- males more often
- like local Coats’
- laser helps in type 1 only
II) bilateral parafoveal
- SRNV as complication
- most common
associations:
1) small, yellow lesions within the FAZ
2) right-angle retinal venules
3) stellate plaques of RPE hyperplasia
III) bilateral perifoveal with capillary obliteration
Pars Planitis sequelae
1) cataract
2) glaucoma
3) CME
4) RD
5) VH
6) NV
7) band
8) phthisis
9) disc edema
PHPV
(retrol. mass of fat, SM, collagen, cartil.)
1) microphthalmos, microcornea
2) cataract
3) angle closure glaucoma
4) usually unilateral
5) elongated ciliary processes
Pigment dispersion syndrome
1) M > F; W > B
2) young
3) myope
4) Krukenberg spindle
5) lens, angle, iris, zonule pigment deposits
6) midperipheral atrophic spokes
7) worse after exercise (dilation)
8) glaucoma develops in 33% (one third)
9) may be steroid responders (1 study yes, 1 no)
10) may be related to COAG (1 study yes, 1 no)
11) blinking causes increased IOP (pupil block?)
12) Tx: PI, pilo (usually not tolerated), IOP control, ALT
Plateau Iris
1) deep central AC
2) narrow angle
3) configuration: PI curative
4) syndrome: PI not curative
Posner Schlossman
1) recurrent
2) IOP 40-60
3) due to PG abnormality
4) ciliary flush
5) mild AC rxn
6) sluggish pupil
7) epithelial edema
8) flare and a few KP’s
10) no PAS
11) some have steroid response like COAG
12) Tx. steroids, NSAIDs (when to treat?)
Posterior Polymorphous Dystrophy
- AD or AR
1) broad bands with scalloped edge
2) gray geographic lesions
3) stromal edema
4) corectopia
5) iridocorneal adhesions
Posterior scleritis
1) pain
2) proptosis
3) visual loss
4) restricted EOM movements
5) lower lid retraction on upgaze
6) choroidal folds
7) exudative RD
8) papilledema
9) ACG
10) posterior uveitis (vitritis)
11) thickening on CT/MRI
12) sometimes associated TB or c.t. disease
Reis Buckller’s
- AD
1) areas of absent epith b.m
2) recurrent erosions
3) recurrence in graft
4) subepithelial honeycomb pattern
5) scarring
Retinopathy of Prematurity
1) myopia
2) RD
3) glaucoma
4) cataract
5) phthisis bulbi
Retinoschisis - Congenital
1) macular schisis (100%)
2) peripheral schisis (50%)
3) vitreous vascular veils
4) poor vision
5) nystagmus
6) strabismus
7) vitreous hemorrhage
8) normal EOG, decreased b wave on ERG
Shaken baby syndrome (order of frequency)
1) intraocular hemorrhage (preretinal and retinal heme)
2) lid ecchimosis
3) RD, retinal dialysis
4) cataract/subluxated lens
5) papilledema / optic atrophy
6) subconj. heme
7) esotropia
Spasmus Nutans
1) unilateral or bilateral nystagmus
2) begins before 1 year
3) usually finishes prior to 3 years
4) no nystagmus during sleep
5) torticollis
6) head nodding
7) begins between 4 and 18 months of age
8) horizontal, torsional, or vertical nystagmus
Spherophakia
Associations: Marfan’s, Weil Marchesani
Findings
1) myopia
2) pupil block, worse with miotics
3) Tx: mydriatics
Stargardt’s (“juvenile mac deg.”)
- most common hereditary maculopathy
- AR
1) present as young children
2) vision decreases to 20/200 by age 20, but one eye may remain 20/70 -20/100
3) pattern ERG: abnormal
4) full field ERG: ?
5) EOG: normal ?
Superior limbic keratitis
1) F > M
2) recurs over 1-10 years
3) often bilateral
4) papillary rxn
5) thickened superior limbus
6) staining of superior conj.
7) filaments
8) associated with thyroid (50%)
Terrien’s marginal degeneration
1) unil or bilateral
2) 20-40 y.o.
3) begin’s at 12:00
4) epithelium intact
5) pannus over area of thinning
6) perforation with mild trauma
7) lipid line at anterior edge
8) against the rule astigmatism (like wound gape)
9) Tx: lamellar graft
Thygeson’s SPK (1950)
1) multiple gray/granular epithelial opacities
2) lesions stain with both fluorescein and rose bengal (mild fluor. stainig?) - minimal staining with fluo.
3) quiet eye
4) rare subepithelial opacity
5) usually bilateral
6) symptoms: f.b. sensation, reduced vision, photophobia
7) recurrent episodes
8) respond to steroids or CL